2-Amino-6-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde CAS 1804461-00-4
| CAS No. | 1804461-00-4 |
| Molecular Formula | C8H7BrF2N2O |
| Molecular Weight | 265.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-6-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Amino-6-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde (CAS 1804461-00-4) is a high-purity analytical reference standard with the molecular formula C8H7BrF2N2O and a molecular weight of 265.05 g/mol.
Based on its molecular formula C8H7BrF2N2O, 2-Amino-6-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.05 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-6-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2N2O |
| Molecular Weight | 265.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-5-(bromomethyl)-3-(difluoromethyl)isonicotinaldehyde (CAS 1804460-94-3)
- 2-Amino-5-(bromomethyl)-4-(difluoromethyl)nicotinaldehyde (CAS 1805235-74-8)
- 2-Amino-4-(bromomethyl)-5-(difluoromethyl)nicotinaldehyde (CAS 1805345-66-7)
- 2-Amino-6-(bromomethyl)-3-(difluoromethyl)isonicotinaldehyde (CAS 1805345-72-5)
- 2-Amino-5-bromo-3-(trifluoromethyl)benzonitrile (CAS 1000571-53-8)
- 2-Amino-3-bromo-5-(trifluoromethyl)benzonitrile (CAS 133013-30-6)
- 4-Amino-5-bromo-2-(trifluoromethyl)benzonitrile (CAS 155255-45-1)
- 2-Amino-4-bromo-3-(trifluoromethyl)benzonitrile (CAS 1804405-55-7)
Recommended Standards
- 2-(Aminomethyl)-3-bromo-5-(difluoromethyl)pyridine-6-carboxaldehyde (CAS 1804487-29-3)
- Ethyl 2-bromo-3,6-difluorobenzoate (CAS 1804408-94-3)
- Ethyl 2-bromo-3,5-difluorobenzoate (CAS 1804909-80-5)
- Methyl 2-(3-bromo-4,5-difluorophenyl)acetate (CAS 1804403-26-6)
- Daturataturin A aglycone (CAS 904665-71-0)
- C5a Anaphylatoxin (37-53) (human) (CAS 706808-05-1)
- 2-{[(4-Bromophenyl)amino]methyl}-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione (CAS 430432-41-0)
- (5-methyl-2-pyridyl)hydrazine;hydrochloride (CAS 1375477-15-8)
- 3-chloro-8-iodo-naphthalen-1-amine (CAS 2387595-79-9)
- H-Orn-Orn-Orn-OH (CAS 40681-82-1)
- (2E)-3-{[4-(phenylamino)phenyl]amino}-2-(1H-1,2,3,4-tetrazol-5-yl)prop-2-enenitrile (CAS 683799-78-2)
- 6-Chloro-1H-pyrrolo[3,2-c]pyridin-3-amine (CAS 1190320-39-8)
- (pHenylamino)thiourea (CAS 645-48-7)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com