2-{[(4-Bromophenyl)amino]methyl}-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione CAS 430432-41-0
| CAS No. | 430432-41-0 |
| Molecular Formula | C16H15BrN2O2 |
| Molecular Weight | 347.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.21 g/mol gives 2-{[(4-Bromophenyl)amino]methyl}-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-{[(4-Bromophenyl)amino]methyl}-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione (CAS 430432-41-0), a certified reference material (molecular formula C16H15BrN2O2, MW 347.21 g/mol) for analytical method development and quality control.
2-{[(4-Bromophenyl)amino]methyl}-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione (C16H15BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15BrN2O2 |
| Molecular Weight | 347.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenyl Standards
- 5-((4-Bromophenyl)sulfonyl)-2-mercaptopyrimidin-4-ol (CAS 1255776-64-7)
- (2E)-3-(3-Bromophenyl)-1-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 1002849-71-9)
- (2E)-3-(4-Bromophenyl)-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1021493-90-2)
- (2E)-3-(3-Bromophenyl)-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 119199-31-4)
- (2E)-1-(3-Bromophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1352347-04-6)
- (2E)-1-(4-Bromophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (CAS 158575-03-2)
- (2E)-1-(4-Bromophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1646177-46-9)
- (2E)-1-(3-Bromophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (CAS 358656-12-9)
Recommended Standards
- 1-Morpholino-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethanone (CAS 656257-49-7)
- 4-(2-Bromo-5-methoxyphenyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one (CAS 2173253-12-6)
- 1-Morpholino-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethanone (CAS 2057448-28-7)
- 4-(3-Bromo-4-methoxyphenyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one (CAS 2173253-16-0)
- 2-(((4-Bromophenyl)thio)methyl)-4-chloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine (CAS 885459-34-7)
- 4-[4-(2-Thienyl)-2-pyrimidinyl]phenyl benzenecarboxylate (CAS 477862-90-1)
- N-(4-chlorophenyl)-2,8-dimethylimidazo[1,2-a]pyridine-3-carboxamide (CAS 241146-69-0)
- 4-[(3-cyclobutyl-1,2,4-oxadiazol-5-yl)methyl]piperidine hydrochloride (CAS 1909327-75-8)
- 6-Methyl-2-pivalamidonicotinic acid (CAS 1359763-35-1)
- 1,3-Dibromo-2,4-difluoro-6-iodobenzene (CAS 1000577-95-6)
- 1-[4-Amino-7-(3-tert-butyldimethylsilyloxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 821794-84-7)
- 2-Iodo-5-trifluoromethyl-pyridine (CAS 100366-75-4)
- Benzyl 2-cyano-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 1416712-45-2)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com