2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carboxylic acid CAS 1804625-12-4
| CAS No. | 1804625-12-4 |
| Molecular Formula | C9H5BrF5NO3 |
| Molecular Weight | 350.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carboxylic acid (CAS 1804625-12-4), a certified reference material (molecular formula C9H5BrF5NO3, MW 350.04 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 350.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrF5NO3 |
| Molecular Weight | 350.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 2-(Bromomethyl)-6-(difluoromethyl)-3-(trifluoromethoxy)pyridine-4-carboxylic acid (CAS 1805144-45-9)
- 2-(Bromomethyl)-4-(difluoromethyl)-3-(trifluoromethoxy)pyridine-5-carboxylic acid (CAS 1805235-23-7)
- 2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-4-carboxylic acid (CAS 1805302-30-0)
- 4-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)picolinic acid (CAS 1806765-34-3)
- 5,5-Bis(bromomethyl)-2-phenyl-1,3-dioxane (CAS 3733-29-7)
- N-(4-(Bromomethyl)-3-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (CAS 630125-84-7)
- 5-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole (CAS 1184953-71-6)
- 2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole (CAS 337508-54-0)
Recommended Standards
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- Li Standard Solution (CAS 7439-93-2)
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