Belumosudil Impurity 61 CAS CATO-C4X-298861
| CAS No. | CATO-C4X-298861 |
| Molecular Formula | C12H8Cl4N4 |
| Molecular Weight | 350.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Belumosudil Impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Belumosudil Impurity 61 (CAS CATO-C4X-298861), a pharmacopoeial impurity reference standard (molecular formula C12H8Cl4N4, MW 350.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H8Cl4N4, Belumosudil Impurity 61 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 350.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl4N4 |
| Molecular Weight | 350.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Belumosudil Standards
- Belumosudil Impurity 59 (CAS CATO-C4X-298859)
- Belumosudil Impurity 62 (CAS CATO-C4X-298862)
- Belumosudil Impurity 33 (CAS 2121561-37-1)
- Belumosudil Impurity 43 (CAS 2121561-41-7)
- Belumosudil Impurity 35 (CAS CATO-C4X-298835)
- Belumosudil Impurity 44 (CAS CATO-C4X-298844)
- Belumosudil Impurity 38 (CAS CATO-C4X-298838)
- Belumosudil Impurity 39 (CAS 2121561-39-3)
Recommended Standards
- N,N’-bis(3,5-dichlorophenyl)urea (CAS 73439-19-7)
- N,N＇-Bis-(3,4-Dichlorophenyl)Urea (CAS 4300-43-0)
- 4-(2-Aminothiazol-4-yl)-2,6-dibromophenol (CAS 874606-50-5)
- 2-(Bromomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carboxylic acid (CAS 1804625-12-4)
- Ozenoxacin Impurity 56 (CAS CATO-C4X-279656)
- Siponimod impurity 16 (CAS CATO-C4X-247216)
- Atorvastatin Impurity N5 (CAS 1403667-07-1)
- 3,5-Dimethyl-4-(2,2,2-trifluoroethoxy)pyridine 1-oxide (CAS 103577-78-2)
- 5-Chloro-1-ethyl-1H-imidazole-4-carbaldehyde (CAS 62260-62-2)
- 2-(Benzo[d]isoxazol-3-yl)acetonitrile (CAS 50471-17-5)
- 8-Methoxyimidazo[1,2-a]pyrazin-3-amine (CAS 1935022-87-9)
- (3-Methylmorpholin-2-yl)methanol (CAS 2241336-40-1)
- 3-(4-Methoxyphenyl)-2-(4-nitrophenyl)propanenitrile (CAS 1254177-50-8)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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