3-(Difluoromethyl)-5-(trifluoromethyl)pyridin-4-amine CAS 1804655-11-5
| CAS No. | 1804655-11-5 |
| Molecular Formula | C7H5F5N2 |
| Molecular Weight | 212.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(Difluoromethyl)-5-(trifluoromethyl)pyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(Difluoromethyl)-5-(trifluoromethyl)pyridin-4-amine (CAS 1804655-11-5) is a high-purity analytical reference standard with the molecular formula C7H5F5N2 and a molecular weight of 212.12 g/mol.
3-(Difluoromethyl)-5-(trifluoromethyl)pyridin-4-amine (C7H5F5N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5F5N2 |
| Molecular Weight | 212.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3-(trifluoromethoxy)benzene (CAS 1214326-70-1)
- 3-(Difluoromethyl)-5-(trifluoromethyl)phenol (CAS 1261482-74-9)
- 2-(Difluoromethyl)-4-(trifluoromethyl)phenol (CAS 1261500-20-2)
- 4-(Difluoromethyl)-3-(trifluoromethyl)phenol (CAS 1261606-01-2)
- 5-(Difluoromethyl)-2-(trifluoromethyl)phenol (CAS 1261778-70-4)
- 5-(Difluoromethyl)-2-(trifluoromethyl)pyridin-4-amine (CAS 1805173-71-0)
- 3-(Difluoromethyl)-4-(trifluoromethyl)pyridin-2-amine (CAS 1805302-56-0)
- 6-(Difluoromethyl)-3-(trifluoromethyl)pyridin-2-amine (CAS 1805302-67-3)
Recommended Standards
- 2,6-Difluoro-4-(trifluoromethoxy)toluene (CAS 1803828-47-8)
- 2,5-Difluoro-3-(trifluoromethoxy)toluene (CAS 1805056-91-0)
- 4,5-Difluoro-2-(trifluoromethoxy)toluene (CAS 1803732-00-4)
- 2,4-Difluoro-6-(trifluoromethoxy)toluene (CAS 1803731-96-5)
- [4-(4-methylbenzenesulfonyl)phenyl]methanol (CAS 1461713-57-4)
- (S)-2-Amino-1-((S)-2-((benzyl(cyclopropyl)amino)methyl)pyrrolidin-1-yl)-3-methylbutan-1-one (CAS 1401669-18-8)
- 3-(tert-Butyl)-5-cyclopropoxy-2-iodopyridine (CAS 1243461-02-0)
- n-Methyl-2-(4-methylpiperidin-1-yl)acetamide (CAS 1071400-91-3)
- 5-Azaspiro[2.4]heptan-7-ol (CAS 944258-72-4)
- Methyl 2,2-bis(4-Hydroxyphenyl)acetate (CAS 5129-00-0)
- Ethyl 3-oxo-4-(tetrahydrofuran-2-yl)butanoate (CAS 670275-62-4)
- 2-(4-Bromofuran-2-yl)-1,3-dioxolane (CAS 83953-42-8)
- 2-(1-Pyrazolyl)benzylamine (CAS 449758-13-8)
- Hexapeptide-11 (CAS 100684-36-4)
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