4-(Difluoromethyl)-5-fluoro-2-methylpyridine CAS 1804703-89-6

Description

The occurrence of 4-(Difluoromethyl)-5-fluoro-2-methylpyridine is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(Difluoromethyl)-5-fluoro-2-methylpyridine (CAS 1804703-89-6) is a high-purity analytical reference standard with the molecular formula C7H6F3N and a molecular weight of 161.12 g/mol.

The molecular framework of 4-(Difluoromethyl)-5-fluoro-2-methylpyridine (C7H6F3N) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Difluoromethyl)-5-fluoro-2-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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