Ibuprofen EP Impurity M CAS 60057-62-7
| CAS No. | 60057-62-7 |
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ibuprofen EP Impurity M is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ibuprofen EP Impurity M (CAS 60057-62-7, C13H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ibuprofen EP Impurity M (C13H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibuprofen EP Impurity M under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
Related Ibuprofen Standards
- Ibuprofen EP Impurity L (CAS 53949-53-4)
- Ibuprofen Impurity 27 (CAS 53949-54-5)
- Ibuprofen Impurity 53 (CAS CATO-C4X-108253)
- Ibuprofen Methyl Ester (CAS 61566-34-5)
- Ibuprofen EP Impurity J (CAS 65813-55-0)
- Ibuprofen EP Impurity J (CAS CATO-C4X-1082148)
- (S)-(+)-Ibuprofen Acid Chloride (CAS 115588-20-0)
- Ibuprofen Impurity 58 (CAS 80336-66-9)
Recommended Standards
- 1H-Pyrazole-4-carboxaldehyde,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- 4-Antipyrinecarboxaldehyde 4-Formylantipyrine 950-81-2 Antipyraldehyde Antipyrinaldehyd Antipyrine, 4-formyl- Febranine NSC-60408 NSC60408 (CAS 950-81-2)
- Olmesartan Impurity 30 (CAS 157356-73-5)
- 4-(Acetylmethylamino)-1-(3-pyridyl)-1-butanol 4-(Acetylmethylamino)-1-(3-pyridyl)-1-butanol-d6 887352-16-1 N-(4-Hydroxy-4-pyridin-3-yl-butyl)-N-methyl-acetamide N-(4-Hydroxy-4-pyridin-3-yl-butyl)-N-methyl-acetamide-d6 (CAS 887352-16-1)
- Olaparib Impurity 39 (CAS 458535-34-7)
- Atogepant Impurity 83 (CAS CATO-C4X-328583)
- Fluvastatin Impurity 16 (CAS 2117644-62-7)
- Apremilast Impurity 25 (CAS 608142-27-4)
- 2-(3-Isobutyl-1-methyl-1h-1,2,4-triazol-5-yl)propan-1-amine (CAS 1339858-69-3)
- N-(bicyclo[2.2.2]octan-1-yl)acetamide (CAS 63707-73-3)
- 2-(5-Bromo-2-fluorophenyl)-5-(chloromethyl)thiazole (CAS 1599109-29-1)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-methylpyridine-5-acetic acid (CAS 1361842-79-6)
- (R)-3-(3,4-DICHLOROPHENYL)PYRROLIDINE HCL (CAS 1384269-00-4)
- 2-(Piperidin-4-yl)tetrahydrofuran-3-carboxamide (CAS 1934911-20-2)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com