2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridine-5-carboxylic acid CAS 1804797-53-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridine-5-carboxylic acid.

2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridine-5-carboxylic acid (CAS 1804797-53-2), molecular formula C8H4F5NO4 and molecular weight 273.11 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridine-5-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridine-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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