2-(4-Bromo-6-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid CAS 1804884-27-2
| CAS No. | 1804884-27-2 |
| Molecular Formula | C8H5BrF3NO2 |
| Molecular Weight | 284.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Bromo-6-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-Bromo-6-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid (CAS 1804884-27-2) is a high-purity analytical reference standard with the molecular formula C8H5BrF3NO2 and a molecular weight of 284.03 g/mol.
2-(4-Bromo-6-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid (C8H5BrF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Bromo-6-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF3NO2 |
| Molecular Weight | 284.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- Methyl 5-bromo-6-(trifluoromethyl)nicotinate (CAS 1198016-45-3)
- Methyl 3-bromo-5-(trifluoromethyl)picolinate (CAS 1211536-14-9)
- 3-Bromo-6-(trifluoromethyl)pyridine-2-carboxylic Acid Methyl Ester (CAS 1211538-62-3)
- Methyl 4-bromo-6-(trifluoromethyl)picolinate (CAS 1211579-71-3)
- Methyl 5-Bromo-2-(trifluoromethyl)isonicotinate (CAS 1211589-41-1)
- 3-Bromo-5-(trifluoromethyl)pyridine-2-acetic acid (CAS 1214323-86-0)
- Methyl 5-Bromo-3-(trifluoromethyl)pyridine-2-carboxylate (CAS 1214328-84-3)
- 3-Bromo-6-(trifluoromethyl)pyridine-2-acetic acid (CAS 1214374-35-2)
Recommended Standards
- 4-Bromo-3-(difluoromethyl)-2-fluoropyridine-5-acetic acid (CAS 1804852-40-1)
- 2-(6-Bromo-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805029-89-3)
- 2-(2-Bromo-5-(difluoromethyl)-6-fluoropyridin-3-yl)acetic acid (CAS 1804852-26-3)
- 2-(5-Bromo-2-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1805114-70-8)
- 1-((3-Formylphenoxy)methyl)cyclobutane-1-carbonitrile (CAS 1387563-23-6)
- (R)-1-Boc-3-methyl-[1,4]diazepane (CAS 223644-10-8)
- 4,6-Dimethyl-1H-benzo[d]imidazol-2(3H)-one (CAS 102308-68-9)
- N,N'-((Thiobis(ethane-2,1-diyl))bis(1,3,4-thiadiazole-5,2-diyl))bis(2-phenylacetamide) (CAS 314045-39-1)
- 10-Chlorodecanoic acid (CAS 37027-56-8)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-1-(4-fluorophenyl)prop-2-en-1-one (CAS 304896-57-9)
- N-(4-(N-(3,5-bis(trifluoromethyl)phenyl)sulfamoyl)phenyl)acetamide (CAS 339-38-8)
- N,N-Diethyl-N'-(4'-trifluoromethylbiphenyl-4-ylmethyl)-ethane-1,2-diamine (CAS 304694-40-4)
- Methyl 2-(2,4,6-trifluorophenyl)acetate (CAS 954369-86-9)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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