1-(5-Bromo-2-fluoro-3-hydroxyphenyl)ethan-1-one CAS 1804906-24-8
| CAS No. | 1804906-24-8 |
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(5-Bromo-2-fluoro-3-hydroxyphenyl)ethan-1-one (CAS 1804906-24-8), a certified reference material (molecular formula C8H6BrFO2, MW 233.03 g/mol) for analytical method development and quality control.
The molecular framework of 1-(5-Bromo-2-fluoro-3-hydroxyphenyl)ethan-1-one (C8H6BrFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-(5-Bromo-2-fluoro-3-hydroxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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- 2-Bromo-5-fluoro-4-methylbenzoic acid (CAS 1003709-54-3)
- 3-Bromo-5-fluoro-2-methoxybenzaldehyde (CAS 1009093-60-0)
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- 4-Bromo-2-fluorophenylacetic Acid (CAS 114897-92-6)
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Recommended Standards
- 3-Bromo-4-fluoro-2-methoxybenzaldehyde (CAS 1784176-51-7)
- 1-(4-Bromo-3-fluoro-2-hydroxyphenyl)ethanone (CAS 1805533-00-9)
- 1-(3-Bromo-4-fluoro-2-hydroxyphenyl)ethan-1-one (CAS 1784176-42-6)
- 4-Bromo-2-fluoro-3-methoxybenzaldehyde (CAS 1820614-17-2)
- N-(4-((2-((4H-1,2,4-triazol-4-yl)imino)-3-ethyl-4-oxothiazolidin-5-ylidene)methyl)phenyl)acetamide (CAS 478078-12-5)
- Methyl 3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate (CAS 119205-38-8)
- 4-(4-Methoxyphenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1249317-93-8)
- Sofosbuvir Impurity 85 (CAS 1621160-31-3)
- N,N'-(S)-[1,1'-Binaphthalene]-2,2'-diylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS 914497-25-9)
- 1-(5-(Benzyloxy)-2,4-dichlorophenyl)-1,3-dihydro-2H-imidazole-2-thione (CAS 338967-06-9)
- Methyl 3-(N-(3-chloro-4-fluorophenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate (CAS 932464-84-1)
- 2-(4-Methoxyphenyl)-2-(4-methylpiperidin-1-yl)ethan-1-amine (CAS 889939-86-0)
- Beta-oxo-5-chloro-2-pyridinepropanoic acid methyl ester (CAS 1106999-74-9)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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