4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethoxy)nicotinoyl chloride CAS 1805029-63-3
| CAS No. | 1805029-63-3 |
| Molecular Formula | C9H6ClF5N2O2 |
| Molecular Weight | 304.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethoxy)nicotinoyl chloride (CAS 1805029-63-3), molecular formula C9H6ClF5N2O2 and molecular weight 304.60 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H6ClF5N2O2, 4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethoxy)nicotinoyl chloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 304.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Aminomethyl)-6-(difluoromethyl)-2-(trifluoromethoxy)nicotinoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF5N2O2 |
| Molecular Weight | 304.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethoxy)pyridine-6-carbonyl chloride (CAS 1804437-53-3)
- 4-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethoxy)picolinoyl chloride (CAS 1804669-65-5)
- 2-(Aminomethyl)-5-bromo-3-(difluoromethyl)-4-(trifluoromethyl)pyridine (CAS 1804433-74-6)
- 2-(Aminomethyl)-5-bromo-6-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1804667-12-6)
- 2-(Aminomethyl)-4-bromo-3-(difluoromethyl)-6-(trifluoromethyl)pyridine (CAS 1805948-47-3)
- 2-(Aminomethyl)-6-bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1805948-62-2)
- 2-(Aminomethyl)-4-bromo-5-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1806923-05-6)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonamide (CAS 1361468-18-9)
Recommended Standards
- 4-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-isopropylisoxazole (CAS 700835-81-0)
- N-(tert-butyl)-3,6,7-trichloroquinoxalin-2-amine (CAS 281211-09-4)
- N-(4-Bromophenyl)-5-(chloromethyl)-1,3,4-thiadiazol-2-amine (CAS 7118-92-5)
- n-(4-Bromo-2,6-dimethylphenyl)-4-chlorobutanamide (CAS 1021021-78-2)
- 6-(tert-Butyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1027546-34-4)
- 5-(1H-indol-1-ylmethyl)-2-furoic acid (CAS 876881-48-0)
- 5-(3-Amino-1h-1,2,4-triazol-1-yl)-2,2-dimethylpentanenitrile (CAS 1490906-84-7)
- 1-(But-3-yn-1-yl)-2,2-dimethylpyrrolidine (CAS 1341950-94-4)
- 3-(Cyclopropanesulfonamido)propanoic acid (CAS 1203417-07-5)
- Obeticholic Acid Impurity 52 (CAS 60354-42-9)
- 5-Bromo-1-chloro-2,3-difluorobenzene (CAS 1060813-07-1)
- 5,5'-(1,4-Phenylenebis(oxy))dipentanenitrile (CAS 47096-71-9)
- 9-Benzyl-3,9-diazabicyclo[4.2.1]nonan-4-one (CAS 897396-10-0)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
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