2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide CAS 1805058-75-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1805058-75-6
Molecular FormulaC6H4F3N3O4S
Molecular Weight271.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide CAS 1805058-75-6 chemical structure

Description

The occurrence of 2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide (CAS 1805058-75-6), molecular formula C6H4F3N3O4S and molecular weight 271.17 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 271.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4F3N3O4S
Molecular Weight271.17 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

Related Difluoromethyl Standards

Recommended Standards

Why CATO?