2-(Difluoromethyl)-6-iodo-3-(trifluoromethyl)isonicotinonitrile CAS 1805091-91-1
| CAS No. | 1805091-91-1 |
| Molecular Formula | C8H2F5IN2 |
| Molecular Weight | 348.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Difluoromethyl)-6-iodo-3-(trifluoromethyl)isonicotinonitrile (CAS 1805091-91-1) is a high-purity analytical reference standard with the molecular formula C8H2F5IN2 and a molecular weight of 348.01 g/mol.
The molecular framework of 2-(Difluoromethyl)-6-iodo-3-(trifluoromethyl)isonicotinonitrile (C8H2F5IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(Difluoromethyl)-6-iodo-3-(trifluoromethyl)isonicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H2F5IN2 |
| Molecular Weight | 348.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 6-(Difluoromethyl)-5-iodo-3-(trifluoromethyl)picolinonitrile (CAS 1804491-82-4)
- 3-(Difluoromethyl)-5-iodo-4-(trifluoromethyl)picolinonitrile (CAS 1805387-18-1)
- 4-(Difluoromethyl)-3-iodo-6-(trifluoromethyl)picolinonitrile (CAS 1805387-25-0)
- 5-(Difluoromethyl)-4-iodo-3-(trifluoromethyl)picolinonitrile (CAS 1807078-12-1)
- 3-(Difluoromethyl)-5-iodo-2-(trifluoromethyl)isonicotinonitrile (CAS 1807095-63-1)
- 2-(Difluoromethyl)-4-iodo-3-methylpyridine-5-sulfonamide (CAS 1804868-30-1)
- 2-(Difluoromethyl)-3-iodo-4-methylpyridine-5-sulfonamide (CAS 1805089-99-9)
- 2-(Difluoromethyl)-3-iodo-5-methylpyridine-4-sulfonamide (CAS 1805095-11-7)
Recommended Standards
- 2,4-Dichloro-5-[(1E)-[(E)-2-[(4,6-dichloropyridin-3-yl)methylidene]hydrazin-1-ylidene]methyl]pyridine (CAS 1420776-63-1)
- (2,4-Dibromo-6-(difluoromethoxy)phenyl)(methyl)sulfane (CAS 1805121-02-1)
- 4-Cyano-2-(difluoromethyl)-3-iodo-6-(trifluoromethyl)pyridine (CAS 1805922-04-6)
- methyl 4-bromo-2-chloro-5-(chlorosulfonyl)benzoate (CAS 1157673-21-6)
- 2-(1,3-dioxolan-2-yl)acetic acid (CAS 5735-92-2)
- 2,3,4,5-Tetrathiahexane (CAS 5756-24-1)
- 1-((1-Ethyl-1H-pyrazol-4-yl)methyl)-1H-pyrazol-5-amine (CAS 1415719-51-5)
- 2,3,6,7,10,11-Hexakis[(n-octyl)oxy]triphenylene (CAS 70351-87-0)
- 3-((3,4-Dichlorobenzyl)thio)-N-(3,5-dichlorophenyl)thiophene-2-carboxamide (CAS 251096-87-4)
- 6-Chloro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1082040-88-7)
- 2-Cyclopropylprop-2-enoic acid (CAS 13266-09-6)
- 3-(4-Pyridinyl)-1H-pyrazole-5-carboxylic acid hydrochloride (CAS 865610-69-1)
- 2-Aminoperimidine Hydrobromide [Precipitation reagent for SO4] (CAS 40835-96-9)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com