2-(Difluoromethyl)-5-iodo-3-methoxypyridine-6-carboxylic acid CAS 1805095-16-2
| CAS No. | 1805095-16-2 |
| Molecular Formula | C8H6F2INO3 |
| Molecular Weight | 329.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 329.04 g/mol gives 2-(Difluoromethyl)-5-iodo-3-methoxypyridine-6-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Difluoromethyl)-5-iodo-3-methoxypyridine-6-carboxylic acid (CAS 1805095-16-2) is a high-purity analytical reference standard with the molecular formula C8H6F2INO3 and a molecular weight of 329.04 g/mol.
Based on its molecular formula C8H6F2INO3, 2-(Difluoromethyl)-5-iodo-3-methoxypyridine-6-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Difluoromethyl)-5-iodo-3-methoxypyridine-6-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2INO3 |
| Molecular Weight | 329.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- Methyl 2-(difluoromethyl)-5-iodo-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 1706432-28-1)
- 2-(Difluoromethyl)-3-hydroxy-6-iodopyridine-4-acetic acid (CAS 1804859-34-4)
- 2-(Difluoromethyl)-3-iodo-5-methoxypyridine-4-carboxylic acid (CAS 1804862-59-6)
- 2-(6-(Difluoromethyl)-2-hydroxy-5-iodopyridin-3-yl)acetic acid (CAS 1805064-32-7)
- 4-(Difluoromethyl)-5-iodo-3-methoxypicolinic acid (CAS 1805071-23-1)
- 2-(Difluoromethyl)-5-iodo-4-methoxypyridine-3-carboxylic acid (CAS 1805508-00-2)
- 4-(Difluoromethyl)-3-iodo-5-methoxypicolinic acid (CAS 1805508-11-5)
- 4-(Difluoromethyl)-6-iodo-2-methoxynicotinic acid (CAS 1805532-48-2)
Recommended Standards
- 2-(Difluoromethyl)-6-hydroxy-5-iodopyridine-3-acetic acid (CAS 1805537-00-1)
- 2-(4-(Difluoromethyl)-6-hydroxy-5-iodopyridin-3-yl)acetic acid (CAS 1805542-20-4)
- 6,8-Dibromo-3-ethyl-2-methylquinoline (CAS 860789-83-9)
- 4-(Difluoromethyl)-6-iodo-5-methoxynicotinic acid (CAS 1805544-86-8)
- Ethyl 5-(4-ethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 938009-04-2)
- 4-{3-[3-methoxy-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-5-yl}-2-phenyl-1,2-dihydrophthalazin-1-one (CAS 1707728-03-7)
- (1,2,3,4-Tetrahydroisoquinolin-4-yl)methanol (CAS 45999-84-6)
- (S)-2-Amino-N-(2,3-dichlorobenzyl)-N-ethyl-3-methylbutanamide (CAS 1354001-55-0)
- 6-(Trifluoromethyl)-2h-spiro[benzofuran-3,4'-piperidine] hydrochloride (CAS 2197062-24-9)
- Gemfibrozil-d6 (2?2-dimethyl-d6) (CAS 1184986-45-5)
- 3-Cyano-N-methylbenzamide (CAS 363186-09-8)
- 2-Propenoic acid, butyl ester, polymer with N-(hydroxymethyl)-2-methyl-2-propenamide, 2-methyl-2-propenamide and 2-propenenitrile (CAS 25068-04-6)
- ((2-Methylbut-3-yn-2-yl)oxy)benzene (CAS 30504-61-1)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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