4-Amino-3-cyano-6-(difluoromethyl)pyridine-2-sulfonamide CAS 1805111-79-8
| CAS No. | 1805111-79-8 |
| Molecular Formula | C7H6F2N4O2S |
| Molecular Weight | 248.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-3-cyano-6-(difluoromethyl)pyridine-2-sulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-3-cyano-6-(difluoromethyl)pyridine-2-sulfonamide (CAS 1805111-79-8), molecular formula C7H6F2N4O2S and molecular weight 248.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Amino-3-cyano-6-(difluoromethyl)pyridine-2-sulfonamide (C7H6F2N4O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-3-cyano-6-(difluoromethyl)pyridine-2-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F2N4O2S |
| Molecular Weight | 248.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-1-(3-(trifluoromethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone (CAS 1707727-92-1)
- 2-Amino-7-(2,2,2-trifluoroethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1782248-28-5)
- 4-Amino-5-cyano-2-(difluoromethyl)pyridine-3-sulfonamide (CAS 1805329-33-2)
- 4-Amino-7-fluoro-1,3-dihydrofuro[3,4-c]quinoline-8-carboxylic acid (CAS 2774613-67-9)
- 5-Amino-4-methoxy-2-nitrobenzenesulphonic Acid (CAS 6375-05-9)
- 3-{[2-amino-4-(trifluoromethyl)phenyl]amino}propanoic acid (CAS 106484-66-6)
- 2-Amino-N-(2-(trifluoromethoxy)phenyl)propanamide (CAS 1583176-92-4)
- Ethyl 3-amino-6-(trifluoromethyl)pyridine-2-acetate (CAS 1805591-32-5)
Recommended Standards
- 2-((3-Fluoro-4-nitrophenoxy)methyl)pyridine (CAS 179552-79-5)
- 3-Methyl-5-(pentafluorosulfur)benzyl alcohol (CAS 1858256-52-6)
- 6-(Benzyloxy)-2-fluoro-3-nitropyridine (CAS 1881332-30-4)
- 4-(3-Fluorophenyl)-3,4-dihydrofuro[3,4-d]pyrimidine-2,5(1H,7H)-dione (CAS 1707571-65-0)
- 1-Tricyclo(8.2.2.2(4,7))hexadeca-1(13),4,6,10(14),11,15-hexaen-5-yl-ethanone (CAS 10029-00-2)
- (S)-2-Guanidinopropanoic acid (CAS 1758-74-3)
- N-(5-Amino-2,4-dichlorophenyl)benzamide (CAS 1119390-46-3)
- 2-Bromo-4-nitroimidazole (CAS 65902-59-2)
- 1-Methyl-5-phenyl-1h-pyrazol-4-amine (CAS 91858-00-3)
- 3-Ethyl-2-((3-methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)methyl)-4,5-dihydrothiazol-3-ium iodide (CAS 38586-42-4)
- 1-[2-(3-Quinolinyl)phenyl]ethanone (CAS 893739-46-3)
- 3H-imidazo[4,5-c]pyridine-7-carboxylic acid (CAS 1234616-39-7)
- Gefitinib Impurity 11 (CAS 367-21-5)
- Bonemarrow-Derived Mesenchymal Stem Cells Affinity Peptide trifluoroacetate salt (CAS 683750-83-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com