Gefitinib Impurity 11 CAS 367-21-5
| CAS No. | 367-21-5 |
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 145.56 g/mol gives Gefitinib Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gefitinib Impurity 11 (CAS 367-21-5), a pharmacopoeial impurity reference standard (molecular formula C6H5ClFN, MW 145.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Gefitinib Impurity 11 (C6H5ClFN) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Gefitinib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Gefitinib Standards
Recommended Standards
- Afatinib Impurity 38 (CAS 2106-04-9)
- 5-Chloro-2-fluoroaniline (CAS 2106-05-0)
- 5-Chloro-1,3,4-thiadiazole-2-carbonitrile (CAS 195737-25-8)
- 5-Chloro-2-fluoro-4-methylpyridine 5-chloro-2-fluoro-4-picoline 884494-88-6 (CAS 884494-88-6)
- Difenidol Impurity 7 DiHCl (CAS 63114-16-9)
- Prasugrel Impurity 31 (CAS CATO-C4X-108631)
- Nilotinib Impurity 31 (CAS CATO-C4X-125631)
- N-(4-Amino-3-hydroxyphenyl)acetamide (CAS 129697-50-3)
- 7-(5-Bromo-2-fluorophenyl)-5,8-diazaspiro[3.4]octan-6-one (CAS 1272755-91-5)
- 1-Methylnicotinamide Iodide (CAS 6456-44-6)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-5-[2-(methylsulfanyl)phenyl]-1,3,4-oxadiazole (CAS 339015-38-2)
- 5-(Methoxymethyl)-4-{[(2-pyridinylmethyl)amino]methylene}-2,4-dihydro-3H-pyrazol-3-one (CAS 240799-74-0)
- 5-bromo-6-methylpyrazine-2-carbaldehyde (CAS 1545563-81-2)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com