6-Bromo-3-(difluoromethyl)-5-hydroxypicolinonitrile CAS 1805229-77-9
| CAS No. | 1805229-77-9 |
| Molecular Formula | C7H3BrF2N2O |
| Molecular Weight | 249.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-3-(difluoromethyl)-5-hydroxypicolinonitrile (CAS 1805229-77-9), molecular formula C7H3BrF2N2O and molecular weight 249.01 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H3BrF2N2O, 6-Bromo-3-(difluoromethyl)-5-hydroxypicolinonitrile contains an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 249.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Bromo-3-(difluoromethyl)-5-hydroxypicolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3BrF2N2O |
| Molecular Weight | 249.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 5-Bromo-3,3-difluoro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1393540-54-9)
- 2-Bromo-5-(difluoromethyl)-3-hydroxyisonicotinonitrile (CAS 1805009-61-3)
- 6-Bromo-4-(difluoromethyl)-5-hydroxypicolinonitrile (CAS 1805009-85-1)
- 4-Bromo-3-cyano-2-(difluoromethyl)-6-hydroxypyridine (CAS 1805010-18-7)
- 2-Bromo-5-(difluoromethyl)-4-hydroxynicotinonitrile (CAS 1805229-39-3)
- 2-Bromo-5-(difluoromethyl)-6-hydroxynicotinonitrile (CAS 1805229-45-1)
- 2-Bromo-3-(difluoromethyl)-6-hydroxyisonicotinonitrile (CAS 1805437-65-3)
- 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinonitrile (CAS 1805437-86-8)
Recommended Standards
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- 5-Iodonicotinic acid (CAS 15366-65-1)
- N2,6-Dimethylpyrimidine-2,4,5-triamine (CAS 807262-55-1)
- 383907-42-4 Trisammonium (2R)-2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxy}-3-(octadecanoyloxy)propyl (1R,3S)-2,3,6-trihydroxy-4,5-bis[(hydroxyphosphinato)oxy]cyclohexyl phosphate DTXSID30677087 (CAS 383907-42-4)
- 1,2-Diphenylprop-2-en-1-one (CAS 4452-11-3)
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- 2-[(2,3-dichlorophenyl)formamido]propanoic acid (CAS 1396978-97-4)
- 4-Chloro-2,5-difluorobenzenesulfinic acid sodium salt (CAS 1233506-31-4)
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