2-(Difluoromethyl)-3-methylpyridin-4-amine CAS 1805301-69-2

Description

The occurrence of 2-(Difluoromethyl)-3-methylpyridin-4-amine is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Difluoromethyl)-3-methylpyridin-4-amine (CAS 1805301-69-2) is a high-purity analytical reference standard with the molecular formula C7H8F2N2 and a molecular weight of 158.15 g/mol.

The molecular framework of 2-(Difluoromethyl)-3-methylpyridin-4-amine (C7H8F2N2) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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