2-Bromo-3-(difluoromethyl)-5-methoxy-6-methylpyridine CAS 1805348-30-4
| CAS No. | 1805348-30-4 |
| Molecular Formula | C8H8BrF2NO |
| Molecular Weight | 252.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 252.06 g/mol gives 2-Bromo-3-(difluoromethyl)-5-methoxy-6-methylpyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Bromo-3-(difluoromethyl)-5-methoxy-6-methylpyridine (CAS 1805348-30-4) is a high-purity analytical reference standard with the molecular formula C8H8BrF2NO and a molecular weight of 252.06 g/mol.
The molecular framework of 2-Bromo-3-(difluoromethyl)-5-methoxy-6-methylpyridine (C8H8BrF2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-3-(difluoromethyl)-5-methoxy-6-methylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BrF2NO |
| Molecular Weight | 252.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-(Aminomethyl)-6-bromo-4-(difluoromethyl)pyridin-2-amine (CAS 1805334-32-0)
- 2-Bromo-5-(difluoromethyl)-3-methoxy-4-methylpyridine (CAS 1805351-52-3)
- (4-Bromo-2-(difluoromethyl)-5-methylpyridin-3-yl)methanol (CAS 1805248-18-3)
- 2-Bromo-3-(difluoromethyl)-4-methoxy-5-methylpyridine (CAS 1805416-97-0)
- 1,1,1,5,5,5-Hexamethyl-3-(2-(triethoxysilyl)ethyl)-3-((trimethylsilyl)oxy)trisiloxane (CAS 1356114-66-3)
- Styrene (CAS 100-42-5)
- 2,2,2-trifluoroethyl 3-chloro-4-methoxyphenylcarbamate (CAS 311316-81-1)
- N-(5-nitro-1H-indazol-3-yl)benzamide (CAS 599183-43-4)
- 3-Amino-2-[(2-aminoethyl)amino]benzoic acid (CAS 394655-20-0)
- Tribromochloromethane (CAS 594-15-0)
- N-(2-(piperidin-1-yl)ethyl)cyclohexanamine (CAS 857377-40-3)
- 3-Bromo-1-ethyl-5-nitropyridin-2(1H)-one (CAS 74937-42-1)
- 3-(tert-butyl)-4-(4-chlorophenyl)-2-[2-chloro-5-(trifluoromethyl)anilino]-1,3-thiazol-3-ium bromide (CAS 849066-33-7)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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