3-Chloro-4-(difluoromethyl)-5-methylpyridin-2-amine CAS 1805348-53-1
| CAS No. | 1805348-53-1 |
| Molecular Formula | C7H7ClF2N2 |
| Molecular Weight | 192.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.59 g/mol gives 3-Chloro-4-(difluoromethyl)-5-methylpyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-4-(difluoromethyl)-5-methylpyridin-2-amine (CAS 1805348-53-1), a certified reference material (molecular formula C7H7ClF2N2, MW 192.59 g/mol) for analytical method development and quality control.
3-Chloro-4-(difluoromethyl)-5-methylpyridin-2-amine (C7H7ClF2N2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClF2N2 |
| Molecular Weight | 192.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (3-Chloro-2,6-difluorobenzyl)hydrazine (CAS 1000805-99-1)
- (R)-2-Chloro-2,2-difluoro-1-phenylethan-1-ol (CAS 119454-39-6)
- 1-chloro-2-(difluoromethoxy)-4-methylbenzene (CAS 1225665-64-4)
- (S)-2-Chloro-2,2-difluoro-1-phenylethan-1-ol (CAS 124095-23-4)
- 4-Chloro-2-(difluoromethoxy)-1-methylbenzene (CAS 1261449-29-9)
- 4-Chloro-1-(difluoromethyl)-2-methoxybenzene (CAS 1261449-35-7)
- 2-Chloro-1-(difluoromethoxy)-4-methyl-benzene (CAS 1261554-69-1)
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Recommended Standards
- 6-Chloro-3-(difluoromethyl)-4-methylpyridin-2-amine (CAS 1805326-12-8)
- 1-Chloro-2,6-difluoro-3-ethoxybenzene (CAS 1805526-83-3)
- 3-Chloro-6-(difluoromethyl)-4-methylpyridin-2-amine (CAS 1805325-96-5)
- 6-Chloro-2-(difluoromethyl)-3-methylpyridin-4-amine (CAS 1805922-27-3)
- 2-Bromo-4-fluoro-6-(trifluoromethyl)benzoic acid (CAS 2091606-46-9)
- 5-Amino-4-cyano-1-(4-chlorophenyl)-3-methylpyrazole (CAS 58791-82-5)
- Ethyl 2-amino-6-chloro-3-methylbenzoate (CAS 1183546-09-9)
- 4-(3-Azetidinyl)quinoline (CAS 1260869-41-7)
- N-(4-bromo-2,5-difluoro-phenyl)-6-chloro-1H-pyrrolo[2,3-b]pyridine-3-sulfonamide (CAS 2231232-39-4)
- 1-(2-Hydroxyethyl)-3-nitro-1H-pyrazole-4-carboxamide (CAS 39205-83-9)
- D-Arginine 1,1-Dimethylethyl Ester (CAS 130752-28-2)
- Methyl 4-(5-nitro-1-benzothiophene-2-amido)benzoate (CAS 478248-48-5)
- Metaraminol Impurity 21 (CAS 1602857-94-2)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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