2-Chloro-5-(difluoromethyl)-3-nitropyridine-4-sulfonamide CAS 1805367-98-9
| CAS No. | 1805367-98-9 |
| Molecular Formula | C6H4ClF2N3O4S |
| Molecular Weight | 287.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Chloro-5-(difluoromethyl)-3-nitropyridine-4-sulfonamide (CAS 1805367-98-9), a certified reference material (molecular formula C6H4ClF2N3O4S, MW 287.63 g/mol) for analytical method development and quality control.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-5-(difluoromethyl)-3-nitropyridine-4-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 287.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-Chloro-5-(difluoromethyl)-3-nitropyridine-4-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2N3O4S |
| Molecular Weight | 287.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5-(difluoromethyl)-3-nitropyridine-2-sulfonamide (CAS 1805272-96-1)
- 4-Chloro-6-(difluoromethyl)-5-nitropyridine-3-sulfonamide (CAS 1805368-39-1)
- 6-Chloro-5-(difluoromethyl)-4-nitropyridine-3-sulfonamide (CAS 1805376-28-6)
- 4-Chloro-3-(difluoromethyl)-5-nitropyridine-2-sulfonamide (CAS 1805414-90-7)
- 6-Chloro-5-(difluoromethyl)-4-nitropyridine-2-sulfonamide (CAS 1807090-60-3)
- 2-Chloro-4-(difluoromethyl)-5-nitropyridine-3-sulfonamide (CAS 1807090-73-8)
- 2-Chloro-6-(pentafluoroethylthio)benzonitrile (CAS 1159512-56-7)
- 1-Chloro-8-nitroanthracene-9,10-dione (CAS 129-38-4)
Recommended Standards
- 4-Amino-6-(difluoromethyl)-3-nitropyridine-2-sulfonyl chloride (CAS 1805357-96-3)
- 4-Amino-2-(difluoromethyl)-5-nitropyridine-3-sulfonyl chloride (CAS 1805014-71-4)
- Hexadecanoic-d31 Acid (CAS 39756-30-4)
- 4-Amino-6-(difluoromethyl)-5-nitropyridine-2-sulfonyl chloride (CAS 1806004-09-0)
- 2-Amino-2-(3,4,5-trifluorophenyl)ethan-1-ol (CAS 870852-79-2)
- [(2-Chloro-6-fluorophenyl)methyl](2-methylpropyl)amine (CAS 869945-17-5)
- (1-(5,6-Di-p-tolyl-1,2,4-triazin-3-yl)piperidin-4-yl)methanol (CAS 88300-46-3)
- 4'-Fluoro-[1,1'-biphenyl]-3-thiol (CAS 141106-53-8)
- 6-Hydroxy-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2305070-03-3)
- 1-(1-p-Tolyl-ethyl)-piperazine (CAS 514789-74-3)
- 5-Benzyl-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl hydrosulfide (CAS 451501-91-0)
- 3-Fluoro-4-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl)aniline (CAS 937597-82-5)
- Ethyl 6-nitro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 30093-88-0)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com