2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-6-acetonitrile CAS 1805428-84-5
| CAS No. | 1805428-84-5 |
| Molecular Formula | C10H6ClF2N3 |
| Molecular Weight | 241.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805428-84-5), a certified reference material (molecular formula C10H6ClF2N3, MW 241.62 g/mol) for analytical method development and quality control.
2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-6-acetonitrile (C10H6ClF2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF2N3 |
| Molecular Weight | 241.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-3-cyano-4-(difluoromethyl)pyridine-5-acetonitrile (CAS 1804422-54-5)
- 2-(Chloromethyl)-3-cyano-4-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805038-42-9)
- 2-(Chloromethyl)-4-cyano-3-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805185-55-0)
- 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806013-00-2)
- 2-(Chloromethyl)-5-cyano-3-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806845-41-9)
- 2-(Chloromethyl)-6-cyano-4-(difluoromethyl)pyridine-3-acetonitrile (CAS 1806845-46-4)
- 2-(Chloromethyl)-6-cyano-5-(difluoromethyl)pyridine-3-acetonitrile (CAS 1806958-29-1)
- 2-(Chloromethyl)-4-cyano-6-(difluoromethyl)pyridine-3-acetonitrile (CAS 1807075-94-0)
Recommended Standards
- 5-Chloro-2-(2-fluoropyridin-4-yl)pyrimidine-4,6(1H,5H)-dione (CAS 1822822-23-0)
- 4-Amino-7-chloro-6-fluorocinnoline-3-carboxylic acid (CAS 159831-73-9)
- 2-(2-Chloro-4-fluorophenyl)-3,3,3-trifluoropropan-1-amine (CAS 1513642-82-4)
- 2-Chloro-N-(3,4-difluorophenyl)pyrimidin-4-amine (CAS 919200-67-2)
- 2-benzyl-3-methylbutanoic acid (CAS 53483-11-7)
- N-(4-Butylphenyl)-3-(5-(4-chlorophenyl)furan-2-yl)propanamide (CAS 853312-03-5)
- 2-Bromo-N-(4-fluorobenzyl)acetamide (CAS 190193-10-3)
- N-(2-Aminoethyl)-5-oxo-1-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide (CAS 1081138-72-8)
- 5-(Furan-2-yl)pentanoic acid (CAS 30336-13-1)
- Bis(4-iodophenyl)amine (CAS 20255-70-3)
- 1,3,5-Tribenzhydryl-1,3,5-triazinane (CAS 91290-81-2)
- (1-(5-Chloropyrimidin-2-yl)piperidin-2-yl)methanamine hydrochloride (CAS 1261234-05-2)
- Voriconazole 3-Epimer (CAS CATO-CP114107)
- Akt/SKG Substrate Peptide (CAS 276680-69-4)
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