2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-4-acetonitrile CAS 1806013-00-2
| CAS No. | 1806013-00-2 |
| Molecular Formula | C10H6ClF2N3 |
| Molecular Weight | 241.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806013-00-2), molecular formula C10H6ClF2N3 and molecular weight 241.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-4-acetonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF2N3 |
| Molecular Weight | 241.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-3-cyano-4-(difluoromethyl)pyridine-5-acetonitrile (CAS 1804422-54-5)
- 2-(Chloromethyl)-3-cyano-4-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805038-42-9)
- 2-(Chloromethyl)-4-cyano-3-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805185-55-0)
- 2-(Chloromethyl)-3-cyano-5-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805428-84-5)
- 2-(Chloromethyl)-5-cyano-3-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806845-41-9)
- 2-(Chloromethyl)-6-cyano-4-(difluoromethyl)pyridine-3-acetonitrile (CAS 1806845-46-4)
- 2-(Chloromethyl)-6-cyano-5-(difluoromethyl)pyridine-3-acetonitrile (CAS 1806958-29-1)
- 2-(Chloromethyl)-4-cyano-6-(difluoromethyl)pyridine-3-acetonitrile (CAS 1807075-94-0)
Recommended Standards
- 5-Chloro-2-(2-fluoropyridin-4-yl)pyrimidine-4,6(1H,5H)-dione (CAS 1822822-23-0)
- 2-Chloro-N-(3,4-difluorophenyl)pyrimidin-4-amine (CAS 919200-67-2)
- 4-Amino-7-chloro-6-fluorocinnoline-3-carboxylic acid (CAS 159831-73-9)
- 4-Chloro-2-(difluoromethyl)-7-vinylpyrido[3,2-d]pyrimidine (CAS 2637414-25-4)
- 4-(Difluoromethyl)-6-iodo-5-methoxypyridine-3-sulfonyl chloride (CAS 1805602-91-8)
- 3-methyl-1-(2-methylpropyl)piperazin-2-one (CAS 1214021-50-7)
- (2-Methoxynaphthalen-1-yl)methanamine (CAS 136402-93-2)
- Afatinib Impurity 33 (CAS CATO-C4X-100633)
- 5-Bromo-6-methylpyrimidine-2,4-diol (CAS 15018-56-1)
- Fmoc-Pro(3R-Me)-OH (CAS 928330-94-3)
- 1-(2,4-Dichloro-6-hydroxyphenyl)ethanone (CAS 57051-50-0)
- 3-(Methylamino)-6-nitroquinazolin-4(3H)-one (CAS 60512-88-1)
- 65114-14-9 CTK5C2184 Thiocyanic acid,calcium salt, tetrahydrate (9CI) (CAS 65114-14-9)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com