2-(4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid CAS 1805464-82-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1805464-82-7
Molecular FormulaC10H8F5NO3
Molecular Weight285.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid CAS 1805464-82-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1805464-82-7), molecular formula C10H8F5NO3 and molecular weight 285.17 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 2-(4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8F5NO3
Molecular Weight285.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms1

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