2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine CAS 1805481-12-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1805481-12-2
Molecular FormulaC7H6F2N2O4
Molecular Weight220.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine CAS 1805481-12-2 chemical structure

Description

The molecular framework of 2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine (C7H6F2N2O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine (CAS 1805481-12-2) is a high-purity analytical reference standard with the molecular formula C7H6F2N2O4 and a molecular weight of 220.13 g/mol.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H6F2N2O4
Molecular Weight220.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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