4-(Difluoromethyl)-5-methoxy-2-nitropyridin-3-ol CAS 1805481-18-8
| CAS No. | 1805481-18-8 |
| Molecular Formula | C7H6F2N2O4 |
| Molecular Weight | 220.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(Difluoromethyl)-5-methoxy-2-nitropyridin-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(Difluoromethyl)-5-methoxy-2-nitropyridin-3-ol (CAS 1805481-18-8) is a high-purity analytical reference standard with the molecular formula C7H6F2N2O4 and a molecular weight of 220.13 g/mol.
The molecular framework of 4-(Difluoromethyl)-5-methoxy-2-nitropyridin-3-ol (C7H6F2N2O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F2N2O4 |
| Molecular Weight | 220.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3-hydroxy-6-methoxy-4-nitropyridine (CAS 1804858-38-5)
- 2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-6-methanol (CAS 1804866-49-6)
- 4-(Difluoromethyl)-3-(hydroxymethyl)-5-nitropyridin-2-ol (CAS 1805067-98-4)
- 2-(Difluoromethyl)-6-hydroxy-3-methoxy-4-nitropyridine (CAS 1805202-75-8)
- 2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-4-methanol (CAS 1805205-18-8)
- 2-(Difluoromethyl)-5-hydroxy-3-nitropyridine-6-methanol (CAS 1805206-20-5)
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-methanol (CAS 1805394-17-5)
- 4-(Difluoromethyl)-5-methoxy-3-nitropyridin-2-ol (CAS 1805446-87-0)
Recommended Standards
- 2-(Difluoromethyl)-4-hydroxy-3-methoxy-5-nitropyridine (CAS 1805481-12-2)
- 2-(Difluoromethyl)-3-hydroxy-4-nitropyridine-5-methanol (CAS 1805536-58-6)
- 2-(Difluoromethyl)-6-hydroxy-5-methoxy-3-nitropyridine (CAS 1805544-40-4)
- 2-(Difluoromethyl)-4-hydroxy-6-methoxy-3-nitropyridine (CAS 1805599-18-1)
- 3-(3,3-Difluorocyclobutyl)propan-1-ol (CAS 2228985-15-5)
- Methyl (2R,3S)-3-(4-methoxyphenyl)oxirane-2-carboxylate (CAS 105560-93-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com