4-(Difluoromethyl)-3-fluoro-2-iodo-5-nitropyridine CAS 1805481-19-9
| CAS No. | 1805481-19-9 |
| Molecular Formula | C6H2F3IN2O2 |
| Molecular Weight | 317.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Difluoromethyl)-3-fluoro-2-iodo-5-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(Difluoromethyl)-3-fluoro-2-iodo-5-nitropyridine (CAS 1805481-19-9), molecular formula C6H2F3IN2O2 and molecular weight 317.99 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Difluoromethyl)-3-fluoro-2-iodo-5-nitropyridine (C6H2F3IN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2F3IN2O2 |
| Molecular Weight | 317.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-fluoro-5-iodo-3-nitropyridine (CAS 1804500-27-3)
- 4-(Difluoromethyl)-3-fluoro-2-iodo-6-nitropyridine (CAS 1804500-56-8)
- 2-(Difluoromethyl)-3-fluoro-6-iodo-5-nitropyridine (CAS 1805192-74-8)
- 4-(Difluoromethyl)-2-fluoro-6-iodo-3-nitropyridine (CAS 1805434-47-2)
- 4-(Difluoromethyl)-2-fluoro-3-iodo-5-nitropyridine (CAS 1805508-64-8)
- 2-(Difluoromethyl)-5-fluoro-6-iodo-3-nitropyridine (CAS 1805508-75-1)
- 2-(Difluoromethyl)-4-fluoro-6-iodo-3-nitropyridine (CAS 1806924-89-9)
- 4-(Difluoromethyl)-5-fluoro-2-iodo-3-nitropyridine (CAS 1807085-22-8)
Recommended Standards
- 2-Iiodo-3-nitro-5-(trifluoromethyl)pyridine (CAS 1806489-17-7)
- 2,4,7,9-Tetrachloro-1,10-phenanthroline (CAS 167946-48-7)
- 4-bromo-2-iodo-5-methyl-aniline (CAS 1609264-62-1)
- 4-(4-Bromophenoxy)-1,2-dichlorobenzene (CAS 854259-28-2)
- N-(4-Bromo-2-fluorophenyl)methanesulfonamide (CAS 549490-15-5)
- 1-(Phenylsulfonyl)piperidine-4-carboxamide (CAS 304668-32-4)
- Lenvatinib-d4 (CAS 2264050-65-7)
- 5-(Benzylsulfanyl)-4-(4-chlorophenyl)-1,2,3-thiadiazole (CAS 338408-18-7)
- 3-(2,2-difluoroethoxy)propanoic acid (CAS 1545306-92-0)
- 5-(Piperidin-1-yl)-1,3,4-thiadiazole-2-thiol (CAS 66180-52-7)
- 1-(5-Cyclopropyl-1H-pyrazol-3-yl)piperidine-3-carboxylic acid (CAS 1706819-51-3)
- [(S)-3-(Benzyl-cyclopropyl-amino)-piperidin-1-yl]-acetic acid (CAS 1354001-24-3)
- 4-Cyclodecen-1-one (CAS 26749-90-6)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
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