2-(Chloromethyl)-5-(difluoromethyl)-3-fluoro-4-iodopyridine CAS 1805565-52-9

Description

2-(Chloromethyl)-5-(difluoromethyl)-3-fluoro-4-iodopyridine (CAS 1805565-52-9) is a high-purity analytical reference standard with the molecular formula C7H4ClF3IN and a molecular weight of 321.47 g/mol.

The molecular framework of 2-(Chloromethyl)-5-(difluoromethyl)-3-fluoro-4-iodopyridine (C7H4ClF3IN) is characterized by a nitrile group, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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