4-(Difluoromethyl)-5-iodo-3-nitropyridin-2-ol CAS 1805616-74-3
| CAS No. | 1805616-74-3 |
| Molecular Formula | C6H3F2IN2O3 |
| Molecular Weight | 316.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(Difluoromethyl)-5-iodo-3-nitropyridin-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(Difluoromethyl)-5-iodo-3-nitropyridin-2-ol (CAS 1805616-74-3), molecular formula C6H3F2IN2O3 and molecular weight 316.00 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 4-(Difluoromethyl)-5-iodo-3-nitropyridin-2-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3F2IN2O3 |
| Molecular Weight | 316.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-6-hydroxy-3-iodo-5-nitropyridine (CAS 1805197-20-9)
- 4-(Difluoromethyl)-6-iodo-3-nitropyridin-2-ol (CAS 1805208-11-0)
- 4-(Difluoromethyl)-6-iodo-5-nitropyridin-2-ol (CAS 1805447-71-5)
- 4-(Difluoromethyl)-6-iodo-5-nitropyridin-3-ol (CAS 1805447-80-6)
- 2-(Difluoromethyl)-6-hydroxy-3-iodo-4-nitropyridine (CAS 1806021-86-2)
- 2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine (CAS 1807063-88-2)
- 2-(Difluoromethyl)-3-hydroxy-5-iodo-4-nitropyridine (CAS 1807132-34-8)
- 2-(Difluoromethyl)-6-hydroxy-4-iodo-3-nitropyridine (CAS 1807161-62-1)
Recommended Standards
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (2-bromo-6-methylpyridin-3-yl)boronate (CAS 1309981-30-3)
- 5-bromo-1-(propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole (CAS 2364586-27-4)
- 6,8-Dibromo-2-methylquinolin-4-amine (CAS 96938-27-1)
- 1,4,9,10-Tetrachloroanthracene (CAS 84655-45-8)
- 1-{2-[5-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (CAS 439109-46-3)
- (Z)-11-Octadecen-1-ol (CAS 62972-93-4)
- 6-(4-Methoxyphenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 938001-71-9)
- 1-(1,3-Benzodioxol-5-Yl)-2,2-Difluoroethanone (CAS 437552-71-1)
- 2-(4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)acetonitrile (CAS 5466-71-7)
- 1-(4-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-N-methylmethanamine (CAS 937796-07-1)
- 3-bromanyl-4-[4-(phenylmethyl)piperazin-1-yl]benzaldehyde 3-bromo-4-[4-(phenylmethyl)-1-piperazinyl]benzaldehyde 443777-04-6 A826560 (CAS 443777-04-6)
- 2-(methoxycarbonyl)phenyl isocyanate (CAS 1793-07-3)
- Benzyl (3-amino-2-hydroxypropyl)carbamate (CAS 749825-45-4)
- Tirzepatide (CAS 2023788-19-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com