2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine CAS 1807063-88-2
| CAS No. | 1807063-88-2 |
| Molecular Formula | C6H3F2IN2O3 |
| Molecular Weight | 316.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine (CAS 1807063-88-2), a certified reference material (molecular formula C6H3F2IN2O3, MW 316.00 g/mol) for analytical method development and quality control.
Structurally, 2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine (C6H3F2IN2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 316.00 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Difluoromethyl)-6-hydroxy-5-iodo-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3F2IN2O3 |
| Molecular Weight | 316.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-6-hydroxy-3-iodo-5-nitropyridine (CAS 1805197-20-9)
- 4-(Difluoromethyl)-6-iodo-3-nitropyridin-2-ol (CAS 1805208-11-0)
- 4-(Difluoromethyl)-6-iodo-5-nitropyridin-2-ol (CAS 1805447-71-5)
- 4-(Difluoromethyl)-6-iodo-5-nitropyridin-3-ol (CAS 1805447-80-6)
- 4-(Difluoromethyl)-5-iodo-3-nitropyridin-2-ol (CAS 1805616-74-3)
- 2-(Difluoromethyl)-6-hydroxy-3-iodo-4-nitropyridine (CAS 1806021-86-2)
- 2-(Difluoromethyl)-3-hydroxy-5-iodo-4-nitropyridine (CAS 1807132-34-8)
- 2-(Difluoromethyl)-6-hydroxy-4-iodo-3-nitropyridine (CAS 1807161-62-1)
Recommended Standards
- 5-bromo-1-(propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole (CAS 2364586-27-4)
- 1,4,9,10-Tetrachloroanthracene (CAS 84655-45-8)
- 1,5,9,10-Tetrachloroanthracene (CAS 82843-47-8)
- 3-Iodo-4-(trifluoromethyl)benzoic acid (CAS 1034690-61-3)
- 3,4-dimethylpyridazine (CAS 68206-10-0)
- 2,3-Difluoro-4-nitroaniline (CAS 1781140-23-5)
- 5-(Oxiran-2-ylmethyl)benzo[d][1,3]dioxole (CAS 7470-44-2)
- 4-((2-(Cyclohex-1-en-1-yl)ethyl)amino)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 866040-07-5)
- (2E)-3-(4-Chlorophenyl)-1-(2,4-dimethylphenyl)prop-2-en-1-one (CAS 284665-99-2)
- 2-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-4(1H)-one (CAS 159639-80-2)
- (S)-Methyl 1-cyano-5-oxopyrrolidine-2-carboxylate (CAS 367906-53-4)
- 5-Bromo-2-(piperidin-3-yloxy)pyridine (CAS 1250803-96-3)
- 1-Piperidinecarboxylicacid, 4-(4-chlorophenyl)-4-hydroxy-, ethyl ester 23482-33-9 CTK4F1555 (CAS 23482-33-9)
- Neuropeptide S (human) (CAS 412938-67-1)
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