2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-4-sulfonamide CAS 1805618-32-9
| CAS No. | 1805618-32-9 |
| Molecular Formula | C6H5F2N3O5S |
| Molecular Weight | 269.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-4-sulfonamide (C6H5F2N3O5S) contains a carbohydrate-derived structure, an amide group, a sulfone group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 269.18 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-4-sulfonamide (CAS 1805618-32-9), molecular formula C6H5F2N3O5S and molecular weight 269.18 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F2N3O5S |
| Molecular Weight | 269.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-sulfonamide (CAS 1805094-04-5)
- 4-(Difluoromethyl)-6-hydroxy-3-nitropyridine-2-sulfonamide (CAS 1807003-92-4)
- 4-(Difluoromethyl)-5-hydroxy-3-nitropyridine-2-sulfonamide (CAS 1807004-09-6)
- 2-(Difluoromethyl)-6-hydroxy-3-nitropyridine-5-sulfonamide (CAS 1807123-72-3)
- 4-(Difluoromethyl)-6-hydroxy-5-nitropyridine-3-sulfonamide (CAS 1807123-79-0)
- 4-(difluoromethyl)-2-(4-methoxyphenyl)-1,3-oxazole-5-carboxylic acid (CAS 1803584-52-2)
- Ethyl 2-(difluoromethyl)-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate (CAS 1708288-63-4)
- 2-(Difluoromethyl)-6-methylpyridine-4-boronic Acid Pinacol Ester (CAS 1321518-16-4)
Recommended Standards
- (1-(3-Bromophenyl)cyclohexyl)methanol (CAS 1781895-37-1)
- 1-((5-Bromopyridin-2-yl)methyl)azepane (CAS 1708414-70-3)
- 1,2,3-Trifluoro-5-(4-nitrophenoxy)benzene (CAS 1706437-46-8)
- Phenyl(3-(trifluoromethyl)phenyl)phosphine oxide (CAS 1643-92-1)
- 6-Chloro-5-isopropylpyrimidine-2,4-diol (Impurity) (CAS 96796-80-4)
- (1-(sec-Butyl)piperidin-4-yl)methanamine (CAS 1247409-53-5)
- (5-Cyclopropylisoxazol-3-yl)methanamine (CAS 1060817-49-3)
- 2-(Propylamino)quinazolin-4(3H)-one (CAS 1791-48-6)
- 1-(1-(Difluoromethyl)-1H-pyrazol-3-yl)-N-((1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl)methanamine hydrochloride (CAS 1856042-77-7)
- 3-Methyl-5-phenyl-4,5-dihydroisoxazol-5-ol (CAS 24334-85-8)
- Ertapenem Impurity 18 (CAS CATO-C4X-163318)
- Tributyl(ethoxy)stannane (CAS 682-00-8)
- 1-(Pyridin-3-ylcarbamoyl)cyclopropane-1-carboxylic acid (CAS 1250381-57-7)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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