6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-3-ol CAS 1805951-75-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-3-ol.

CATO supplies 6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-3-ol (CAS 1805951-75-0), a certified reference material (molecular formula C7H9F2N3O, MW 189.16 g/mol) for analytical method development and quality control.

Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-3-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 189.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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