2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride CAS 1806061-24-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1806061-24-4
Molecular FormulaC7H2ClF5N2O5S
Molecular Weight356.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride CAS 1806061-24-4 chemical structure

Description

The occurrence of 2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride (CAS 1806061-24-4), molecular formula C7H2ClF5N2O5S and molecular weight 356.61 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C7H2ClF5N2O5S, 2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-4-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H2ClF5N2O5S
Molecular Weight356.61 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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