4,6-Dichloro-5-(methylsulfonyl)pyrimidine CAS 1806304-80-2
| CAS No. | 1806304-80-2 |
| Molecular Formula | C5H4Cl2N2O2S |
| Molecular Weight | 227.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Dichloro-5-(methylsulfonyl)pyrimidine (CAS 1806304-80-2) is a high-purity analytical reference standard with the molecular formula C5H4Cl2N2O2S and a molecular weight of 227.07 g/mol.
The molecular framework of 4,6-Dichloro-5-(methylsulfonyl)pyrimidine (C5H4Cl2N2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,6-Dichloro-5-(methylsulfonyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4Cl2N2O2S |
| Molecular Weight | 227.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,4-Dichloro-6-(methylsulfonyl)pyrimidine (CAS 1048389-45-2)
- 4,5-Dichloro-3-methoxythiophene-2-carboxylic acid (CAS 120715-49-3)
- 2,5-Dichloro-pyridine-3-sulfonic acid amide (CAS 1208081-90-6)
- 4,5-Dichloro-2-(methylsulfonyl)pyrimidine (CAS 1803805-58-4)
- 2,5-Dichloro-4-(methylsulfonyl)pyrimidine (CAS 1806288-80-1)
- 2,4-Dichloro-5-(methylsulfonyl)pyrimidine (CAS 514842-56-9)
- 4,6-Dichloro-2-methylsulfonylpyrimidine (CAS 4489-34-3)
- Methyl 4,5-dichloro-3-hydroxythiophene-2-carboxylate (CAS 96232-70-1)
Recommended Standards
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- 2,6-Dichloro-5-methylnicotinamide (CAS 142266-60-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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