Ethyl 3,5-difluoro-4-methylbenzoate CAS 1806321-00-5
| CAS No. | 1806321-00-5 |
| Molecular Formula | C10H10F2O2 |
| Molecular Weight | 200.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 3,5-difluoro-4-methylbenzoate (CAS 1806321-00-5) is a high-purity analytical reference standard with the molecular formula C10H10F2O2 and a molecular weight of 200.18 g/mol.
The molecular framework of Ethyl 3,5-difluoro-4-methylbenzoate (C10H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ethyl 3,5-difluoro-4-methylbenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O2 |
| Molecular Weight | 200.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 3-(2,3-Difluoro-4-methylphenyl)propanoic acid (CAS 1017779-58-6)
- 3-(3,5-difluoro-4-methoxyphenyl)propanal (CAS 1036396-36-7)
- 3-(2,5-Difluoro-4-methoxyphenyl)propanal (CAS 1036396-47-0)
- methyl 2,2-difluoro-3-phenylpropanoate (CAS 109872-99-3)
- Ethyl 2,4-difluoro-3-methylbenzoate (CAS 1243360-42-0)
- 1-(3,5-Difluoro-2-hydroxyphenyl)butan-1-one (CAS 1249729-33-6)
- Ethyl 2,6-difluoro-4-methylbenzoate (CAS 1337606-88-8)
- Ethyl 3,4-difluoro-2-methylbenzoate (CAS 1352208-34-4)
Recommended Standards
- Ethyl 2,4-difluoro-6-methylbenzoate (CAS 1806307-07-2)
- Methyl 2,4-difluoro-6-methylphenylacetate (CAS 1806334-69-9)
- Methyl 4,5-difluoro-2-methylphenylacetate (CAS 1806289-76-8)
- Methyl 2,5-difluoro-3-methylphenylacetate (CAS 1807192-43-3)
- 2-Hydroxy-2-(2-nitrophenyl)acetic acid (CAS 67603-23-0)
- 3,4,5,5,7-Pentamethoxyflavanone (CAS 479672-30-5)
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- 2-(Furan-3-yl)-1-tosylpiperidine (CAS 1355172-89-2)
- Rocuronium Impurity 55 (CAS CATO-C4X-124255)
- 2-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one (CAS 1006872-82-7)
- Ethyl 4-(((ethyl(phenyl)amino)methylene)amino)benzoate (CAS 65816-20-8)
- Amlodipine Impurity 64 (CAS 27807-84-7)
- 2-(Methoxyimino)acetic acid (CAS 88012-58-2)
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