Cinacalcet Impurity 9 CAS 180635-74-9
| CAS No. | 180635-74-9 |
| Molecular Formula | C10H11F3O |
| Molecular Weight | 204.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cinacalcet Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Cinacalcet Impurity 9 (CAS 180635-74-9), a pharmacopoeial impurity reference standard (molecular formula C10H11F3O, MW 204.19 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cinacalcet Impurity 9 (C10H11F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H11F3O |
| Molecular Weight | 204.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F-containing |
Related Cinacalcet Standards
- Cinacalcet Impurity 18 (CAS 191155-81-4)
- Cinacalcet Impurity 24 (CAS 78573-45-2)
- Cinacalcet Amine (CAS 104774-87-0)
- Cinacalcet Impurity 104 (CAS 1079988-51-4)
- Cinacalcet Impurity 50 (CAS 1034094-54-6)
- Cinacalcet Impurity 66 (CAS 113048-69-4)
- Cinacalcet Impurity 25 (CAS 166947-09-7)
- Cinacalcet Impurity N95 (CAS 376641-58-6)
Recommended Standards
- 5-(4-Fluoro-2-methylphenyl)furan-2-carbaldehyde (CAS 1001010-58-7)
- 5-(2-Fluoro-4-methylphenyl)furan-2-carbaldehyde (CAS 1001010-59-8)
- 4-(1H-1,2,3,4-tetrazol-1-yl)benzohydrazide 750599-23-6 Z55928989 (CAS 750599-23-6)
- Methyl 1-(methylsulfonyl)-1h-pyrazole-3-carboxylate (CAS 1005631-68-4)
- Fluphenazine Decanoate EP Impurity E (CAS CATO-C4X-12314)
- Adefovir Impurity 35 (CAS 260252-89-9)
- Resmetirom impurity 67 (CAS CATO-C4X-291267)
- 1-Bromo-2-(cyclohexyloxy)benzene (CAS 105902-37-2)
- Tert-butyl (2-amino-1-(pyrimidin-4-yl)ethyl)carbamate (CAS 1407049-66-4)
- 2,2-Difluoro-6-Methylbicyclo[2.2.1]Heptane (CAS 161716-74-1)
- 1,3-benzothiazol-6-amine dihydrochloride (CAS 1803581-49-8)
- Cefotaxime Impurity 17 (CAS CATO-C4X-120117)
- (Z)-N-(1-Chloro-1-(2-fluorophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl)benzamide (CAS 1323140-60-8)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
Why CATO?
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