Cinacalcet Impurity 24 CAS 78573-45-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.78573-45-2
Molecular FormulaC10H11F3O
Molecular Weight204.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cinacalcet Impurity 24 CAS 78573-45-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 204.19 g/mol gives Cinacalcet Impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Cinacalcet Impurity 24 (CAS 78573-45-2), a pharmacopoeial impurity reference standard (molecular formula C10H11F3O, MW 204.19 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Cinacalcet Impurity 24 (C10H11F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Cinacalcet Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H11F3O
Molecular Weight204.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentF-containing

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