(5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine CAS 1806751-22-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1806751-22-3
Molecular FormulaC9H9F5N2O2
Molecular Weight272.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine CAS 1806751-22-3 chemical structure

Description

The occurrence of (5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine (CAS 1806751-22-3) is a high-purity analytical reference standard with the molecular formula C9H9F5N2O2 and a molecular weight of 272.17 g/mol.

The molecular framework of (5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine (C9H9F5N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-(Difluoromethyl)-2-methoxy-3-(trifluoromethoxy)pyridin-4-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H9F5N2O2
Molecular Weight272.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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