2-(Difluoromethyl)-5-(trifluoromethyl)pyridine-4-carbonyl chloride CAS 1806809-70-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1806809-70-0
Molecular FormulaC8H3ClF5NO
Molecular Weight259.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-5-(trifluoromethyl)pyridine-4-carbonyl chloride CAS 1806809-70-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(Difluoromethyl)-5-(trifluoromethyl)pyridine-4-carbonyl chloride (CAS 1806809-70-0) is a high-purity analytical reference standard with the molecular formula C8H3ClF5NO and a molecular weight of 259.56 g/mol.

Based on its molecular formula C8H3ClF5NO, 2-(Difluoromethyl)-5-(trifluoromethyl)pyridine-4-carbonyl chloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 259.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H3ClF5NO
Molecular Weight259.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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