4-Amino-5-(difluoromethyl)-6-iodonicotinic acid CAS 1806914-23-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1806914-23-7
Molecular FormulaC7H5F2IN2O2
Molecular Weight314.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Amino-5-(difluoromethyl)-6-iodonicotinic acid CAS 1806914-23-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 314.03 g/mol gives 4-Amino-5-(difluoromethyl)-6-iodonicotinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Amino-5-(difluoromethyl)-6-iodonicotinic acid (CAS 1806914-23-7), molecular formula C7H5F2IN2O2 and molecular weight 314.03 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 4-Amino-5-(difluoromethyl)-6-iodonicotinic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 314.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Amino-5-(difluoromethyl)-6-iodonicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H5F2IN2O2
Molecular Weight314.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms2

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