4-(Difluoromethyl)-5-methoxy-3-nitropicolinic acid CAS 1806962-82-2
| CAS No. | 1806962-82-2 |
| Molecular Formula | C8H6F2N2O5 |
| Molecular Weight | 248.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 248.14 g/mol gives 4-(Difluoromethyl)-5-methoxy-3-nitropicolinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(Difluoromethyl)-5-methoxy-3-nitropicolinic acid (CAS 1806962-82-2), molecular formula C8H6F2N2O5 and molecular weight 248.14 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Difluoromethyl)-5-methoxy-3-nitropicolinic acid (C8H6F2N2O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 248.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6F2N2O5 |
| Molecular Weight | 248.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(4-(Difluoromethyl)-6-hydroxy-5-nitropyridin-2-yl)acetic acid (CAS 1805069-20-8)
- 2-(Difluoromethyl)-6-hydroxy-4-nitropyridine-3-acetic acid (CAS 1805092-83-4)
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-acetic acid (CAS 1805093-82-6)
- 2-(4-(Difluoromethyl)-3-hydroxy-5-nitropyridin-2-yl)acetic acid (CAS 1805094-09-0)
- 2-(Difluoromethyl)-6-hydroxy-5-nitropyridine-3-acetic acid (CAS 1805253-76-2)
- 2-(Difluoromethyl)-5-methoxy-3-nitropyridine-6-carboxylic acid (CAS 1805262-67-2)
- 4-(Difluoromethyl)-3-methoxy-5-nitropicolinic acid (CAS 1805263-05-1)
- 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-5-carboxylic acid (CAS 1805466-18-5)
Recommended Standards
- 6-(Difluoromethyl)-2-methoxy-5-nitronicotinic acid (CAS 1806962-67-3)
- 2-(Difluoromethyl)-3-hydroxy-5-nitropyridine-6-acetic acid (CAS 1807122-81-1)
- 2-(Difluoromethyl)-4-hydroxy-3-nitropyridine-5-acetic acid (CAS 1806884-36-5)
- 2-(Difluoromethyl)-4-methoxy-3-nitropyridine-6-carboxylic acid (CAS 1807138-49-3)
- Tert-butyl 3-(piperidin-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate hydrochloride (CAS 1803561-25-2)
- N-Allyl-2-(Drifluoromethyl)pyridin-4-amine (CAS 1864158-98-4)
- 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride (CAS 95130-23-7)
- Finasteride Impurity 32 (CAS 51872-67-4)
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- 2-(4-Methylthiazol-5-yl)ethyl 2H-chromene-3-carboxylate (CAS 1796991-02-0)
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- Methyl 2,2-Dimethyl-5-hexenoate (CAS 252206-21-6)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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