3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile CAS 1806985-95-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1806985-95-4
Molecular FormulaC8H3F5N2O
Molecular Weight238.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile CAS 1806985-95-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile.

3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile (CAS 1806985-95-4), molecular formula C8H3F5N2O and molecular weight 238.11 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile (C8H3F5N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 238.11 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 3-(Difluoromethyl)-5-hydroxy-4-(trifluoromethyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3F5N2O
Molecular Weight238.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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Why CATO?