4-Cyano-3-(difluoromethyl)-6-hydroxy-2-(trifluoromethyl)pyridine CAS 1806875-91-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1806875-91-1
Molecular FormulaC8H3F5N2O
Molecular Weight238.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Cyano-3-(difluoromethyl)-6-hydroxy-2-(trifluoromethyl)pyridine CAS 1806875-91-1 chemical structure

Description

4-Cyano-3-(difluoromethyl)-6-hydroxy-2-(trifluoromethyl)pyridine (CAS 1806875-91-1) is a high-purity analytical reference standard with the molecular formula C8H3F5N2O and a molecular weight of 238.11 g/mol.

4-Cyano-3-(difluoromethyl)-6-hydroxy-2-(trifluoromethyl)pyridine (C8H3F5N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Cyano-3-(difluoromethyl)-6-hydroxy-2-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H3F5N2O
Molecular Weight238.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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