6-Cyano-5-(difluoromethyl)-2-methylnicotinic acid CAS 1807121-44-3
| CAS No. | 1807121-44-3 |
| Molecular Formula | C9H6F2N2O2 |
| Molecular Weight | 212.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 212.15 g/mol gives 6-Cyano-5-(difluoromethyl)-2-methylnicotinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-Cyano-5-(difluoromethyl)-2-methylnicotinic acid (CAS 1807121-44-3), a certified reference material (molecular formula C9H6F2N2O2, MW 212.15 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H6F2N2O2, 6-Cyano-5-(difluoromethyl)-2-methylnicotinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 212.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Cyano-5-(difluoromethyl)-2-methylnicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F2N2O2 |
| Molecular Weight | 212.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cyano Standards
- 6-Cyano-3-(difluoromethyl)-5-methylpicolinic acid (CAS 1804422-80-7)
- 4-Cyano-3-(difluoromethyl)-5-methoxypyridine-2-carboxaldehyde (CAS 1805424-51-4)
- 2-Cyano-3-(difluoromethyl)-5-methylisonicotinic acid (CAS 1805431-01-9)
- 2-Cyano-6-(difluoromethyl)-4-methylnicotinic acid (CAS 1805431-23-5)
- 4-Cyano-6-(difluoromethyl)-2-methylnicotinic acid (CAS 1805431-63-3)
- 2-(2-Cyano-3-(difluoromethyl)pyridin-4-yl)acetic acid (CAS 1806042-76-1)
- 4-Cyano-2-(difluoromethyl)pyridine-3-acetic acid (CAS 1806764-68-0)
- 6-Cyano-2-(difluoromethyl)-5-methylnicotinic acid (CAS 1806908-68-8)
Recommended Standards
- 4-Cyano-2-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde (CAS 1807085-26-2)
- 4-(3,4-difluorophenyl)-2-oxobut-3-enoic acid (CAS 1807901-46-7)
- 1-(difluoromethyl)-6-nitro-1H-indole (CAS 1878839-79-2)
- (2e)-4-(3,4-Difluorophenyl)-4-oxobut-2-enoic acid (CAS 191014-72-9)
- 2-(((1-Acetylpyrrolidin-3-yl)methyl)amino)acetic acid (CAS 1353944-35-0)
- Methyl 6-Oxohexanoate (CAS 6654-36-0)
- 42-O-tert-Butyldimethylsilyloxyethyl-d4 Rapamycin (CAS 1356839-88-7)
- 2-(3-(tert-Butoxycarbonyl)-3-azaspiro[5.5]undecan-9-yl)acetic acid (CAS 952480-32-9)
- tert-Butyl4-(2-amino-1-phenylethyl)piperazine-1-carboxylate (CAS 444892-54-0)
- 3-[(4-Fluorophenyl)(hydroxy)methyl]phenol (CAS 1514332-73-0)
- N-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methylpropan-2-amine (CAS 2096337-36-7)
- 2-(4,5-Dimethyl-1H-imidazol-1-yl)acetonitrile (CAS 170998-16-0)
- (2-Methoxy-5-(piperidin-4-yl)phenyl)boronic acid (CAS 2225173-44-2)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
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