(4-(Difluoromethyl)-2-fluoro-5-iodopyridin-3-yl)methanol CAS 1807134-40-2
| CAS No. | 1807134-40-2 |
| Molecular Formula | C7H5F3INO |
| Molecular Weight | 303.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(4-(Difluoromethyl)-2-fluoro-5-iodopyridin-3-yl)methanol (CAS 1807134-40-2), molecular formula C7H5F3INO and molecular weight 303.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(Difluoromethyl)-2-fluoro-5-iodopyridin-3-yl)methanol (C7H5F3INO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5F3INO |
| Molecular Weight | 303.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-fluoro-6-iodo-3-methoxypyridine (CAS 1804704-20-8)
- 4-(Difluoromethyl)-2-fluoro-3-iodo-5-methoxypyridine (CAS 1804704-29-7)
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-methanol (CAS 1804705-45-0)
- 2-(Difluoromethyl)-6-fluoro-5-iodopyridine-3-methanol (CAS 1804705-50-7)
- 2-(Difluoromethyl)-5-fluoro-3-iodopyridine-4-methanol (CAS 1805049-78-8)
- 2-(Difluoromethyl)-6-fluoro-4-iodopyridine-3-methanol (CAS 1805049-82-4)
- (4-(Difluoromethyl)-6-fluoro-5-iodopyridin-2-yl)methanol (CAS 1805050-38-7)
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-6-methanol (CAS 1805292-45-8)
Recommended Standards
- 2-(Difluoromethyl)-5-fluoro-3-iodo-6-methoxypyridine (CAS 1807091-99-1)
- 2-Bromo-1-(2,6-difluoro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 1823271-81-3)
- 2-Iodo-5-methoxy-3-(trifluoromethyl)pyridine (CAS 1807053-88-8)
- 5-Iodo-4-methyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 1823943-38-9)
- 2-Methoxy-5-(trifluoromethyl)benzyl alcohol (CAS 685126-89-0)
- N-propyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)acetamide (CAS 2057448-33-4)
- 2,6-Bis(methylthio)benzaldehyde (CAS 918882-53-8)
- Tetrabromobisphenol A-13C12 (CAS 1352876-39-1)
- 3,3,6-Trimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1909327-58-7)
- (3-Propyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)methanamine (CAS 1783686-22-5)
- 1-(tert-Butyl) 2-ethyl (2S,4S)-4-bromo-1,2-pyrrolidinedicarboxylate (CAS 132623-01-9)
- 10-Aminodecylphosphonic acid (CAS 859458-82-5)
- 1266376-73-1 4-Ethylpiperazine-1-carboximidamide sulfate MFCD22421995 (CAS 1266376-73-1)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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