2-(Difluoromethyl)-3-fluoro-5-iodopyridine-4-carbonyl chloride CAS 1807135-07-4
| CAS No. | 1807135-07-4 |
| Molecular Formula | C7H2ClF3INO |
| Molecular Weight | 335.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Difluoromethyl)-3-fluoro-5-iodopyridine-4-carbonyl chloride.
CATO supplies 2-(Difluoromethyl)-3-fluoro-5-iodopyridine-4-carbonyl chloride (CAS 1807135-07-4), a certified reference material (molecular formula C7H2ClF3INO, MW 335.45 g/mol) for analytical method development and quality control.
2-(Difluoromethyl)-3-fluoro-5-iodopyridine-4-carbonyl chloride (C7H2ClF3INO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Difluoromethyl)-3-fluoro-5-iodopyridine-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2ClF3INO |
| Molecular Weight | 335.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-carbonyl chloride (CAS 1804428-49-6)
- 4-(Difluoromethyl)-6-fluoro-2-iodonicotinoyl chloride (CAS 1804706-48-6)
- 2-(Difluoromethyl)-3-fluoro-6-iodopyridine-5-carbonyl chloride (CAS 1805045-39-9)
- 2-(Difluoromethyl)-6-fluoro-5-iodopyridine-3-carbonyl chloride (CAS 1805045-48-0)
- 4-(Difluoromethyl)-5-fluoro-6-iodopicolinoyl chloride (CAS 1805045-67-3)
- 2-(Difluoromethyl)-6-fluoro-3-iodopyridine-4-carbonyl chloride (CAS 1805581-21-8)
- 4-(Difluoromethyl)-2-fluoro-5-iodonicotinoyl chloride (CAS 1805581-63-8)
- 4-(Difluoromethyl)-3-fluoro-5-iodopicolinoyl chloride (CAS 1805581-71-8)
Recommended Standards
- 2-(Difluoromethyl)-6-fluoro-4-iodopyridine-3-carbonyl chloride (CAS 1806924-74-2)
- 2-(Difluoromethyl)-5-fluoro-4-iodopyridine-3-carbonyl chloride (CAS 1807135-11-0)
- 2-(Difluoromethyl)-3-fluoro-4-iodopyridine-5-carbonyl chloride (CAS 1806924-63-9)
- 2-Amino-6-(naphthalen-2-ylthio)quinazoline-4(1H)-thione (CAS 52978-99-1)
- N-(2-Aminoethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide (CAS 820247-10-7)
- N,6-dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine (CAS 1355224-95-1)
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