3-Chloro-2-fluoro-4-(trifluoromethyl)aniline CAS 1807135-05-2
| CAS No. | 1807135-05-2 |
| Molecular Formula | C7H4ClF4N |
| Molecular Weight | 213.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-2-fluoro-4-(trifluoromethyl)aniline (C7H4ClF4N) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-2-fluoro-4-(trifluoromethyl)aniline (CAS 1807135-05-2) is a high-purity analytical reference standard with the molecular formula C7H4ClF4N and a molecular weight of 213.56 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-2-fluoro-4-(trifluoromethyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF4N |
| Molecular Weight | 213.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-fluoro-3-(trifluoromethyl)aniline (CAS 105172-78-9)
- 3-Chloro-2-fluoro-6-(trifluoromethyl)aniline (CAS 1092461-38-5)
- 5-Chloro-2-fluoro-4-(trifluoromethyl)aniline (CAS 114973-23-8)
- 2-Chloro-3-fluoro-4-(trifluoromethyl)aniline (CAS 123418-97-3)
- 2-Chloro-4-fluoro-6-(trifluoromethyl)aniline (CAS 1235439-54-9)
- 4-Chloro-2-fluoro-6-(trifluoromethyl)aniline (CAS 1235441-41-4)
- 2-Chloro-6-fluoro-4-(trifluoromethyl)aniline (CAS 123973-31-9)
- 2-Chloro-4-fluoro-5-(trifluoromethyl)aniline (CAS 125508-25-0)
Recommended Standards
- 4-Chloro-2-fluoro-5-(trifluoromethyl)aniline (CAS 1805524-41-7)
- 3-Chloro-4-fluoro-5-(trifluoromethyl)aniline (CAS 914225-61-9)
- 2-Chloro-5-fluoro-4-(trifluoromethyl)benzenamine (CAS 1805524-30-4)
- 4-Chloro-6-nitroisobenzofuran-1(3H)-one (CAS 1048917-94-7)
- 1-(Aminomethyl)spiro[3.5]Nonan-1-ol (CAS 2107771-37-7)
- 7-Hydroxy-1-methyl-1H-indazole-3-carboxylic Acid (CAS 133841-11-9)
- tert-butyl cis-3-aminocyclobutane-1-carboxylate hydrochloride (CAS 1192549-09-9)
- 1-Benzyl-3-[(4-fluorophenyl)methyl]-5-[(2E)-3-[(4-methoxyphenyl)amino]prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338399-43-2)
- Ethyl 2-Acetyl-4-phenylbutanoate (CAS 5337-63-3)
- 3-Methyl-4-nitro-1H-pyrazol-1-amine (CAS 151588-04-4)
- 4-Ethyl-7,8-dihydroxy-2H-chromen-2-one (CAS 19040-66-5)
- 3-Amino-4-chloro-5-hydroxybenzoic acid (CAS 93561-97-8)
- 2-Bromo-5-(difluoromethyl)-6-hydroxynicotinaldehyde (CAS 1806908-71-3)
- C-Peptide 1 (rat) (CAS 41475-27-8)
Why CATO?
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