2-(Aminomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid CAS 1807151-03-6
| CAS No. | 1807151-03-6 |
| Molecular Formula | C9H9F2IN2O2 |
| Molecular Weight | 342.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Aminomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid.
2-(Aminomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid (CAS 1807151-03-6) is a high-purity analytical reference standard with the molecular formula C9H9F2IN2O2 and a molecular weight of 342.08 g/mol.
2-(Aminomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid (C9H9F2IN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Aminomethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9F2IN2O2 |
| Molecular Weight | 342.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-5-(difluoromethyl)-4-iodopyridine-3-acetic acid (CAS 1805149-18-1)
- 2-(4-(Aminomethyl)-6-(difluoromethyl)-5-iodopyridin-3-yl)acetic acid (CAS 1805199-24-9)
- 2-(4-(Aminomethyl)-5-(difluoromethyl)-2-iodopyridin-3-yl)acetic acid (CAS 1805466-77-6)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-iodopyridine-5-acetic acid (CAS 1805547-31-2)
- 2-(4-(Aminomethyl)-6-(difluoromethyl)-2-iodopyridin-3-yl)acetic acid (CAS 1805554-38-4)
- 2-(Aminomethyl)-4-(difluoromethyl)-5-iodopyridine-3-acetic acid (CAS 1805614-08-7)
- 2-(4-(Aminomethyl)-3-(difluoromethyl)-5-iodopyridin-2-yl)acetic acid (CAS 1806859-42-6)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-iodopyridine-4-acetic acid (CAS 1806956-77-3)
Recommended Standards
- 2-(Aminomethyl)-3-(difluoromethyl)-6-iodopyridine-4-acetic acid (CAS 1806988-80-6)
- 2-(4-(Aminomethyl)-2-(difluoromethyl)-6-iodopyridin-3-yl)acetic acid (CAS 1807152-58-4)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-iodopyridine-4-acetic acid (CAS 1806957-01-6)
- 3-(4-Amino-1,2,5-oxadiazol-3-yl)-4-(3-bromo-4-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one (CAS 914471-43-5)
- 2-Chloro-4-(methoxymethoxy)phenol (CAS 400052-33-7)
- 3-Bromo-5-methyl-4-phenyl-1H-pyrazole (CAS 1231309-82-2)
- 3,3-Difluorooxetane (CAS 33420-50-7)
- 1-[4-(3-Chlorophenyl)-1-piperazinyl]ethanone (CAS 141511-13-9)
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- N-(Tetrahydro-4-hydroxy-1,1-dioxido-3-thienyl)-β-alanine (CAS 325851-81-8)
- Methyl 4-(2-butoxyvinyl)-2-fluorobenzoate (CAS 1352721-91-5)
- Exenatide Acetate (CAS 141732-76-5)
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