1-Bromo-3-nitro-5-(trifluoromethoxy)benzene CAS 1807151-57-0
| CAS No. | 1807151-57-0 |
| Molecular Formula | C7H3BrF3NO3 |
| Molecular Weight | 286.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Bromo-3-nitro-5-(trifluoromethoxy)benzene (CAS 1807151-57-0), a certified reference material (molecular formula C7H3BrF3NO3, MW 286.00 g/mol) for analytical method development and quality control.
The molecular framework of 1-Bromo-3-nitro-5-(trifluoromethoxy)benzene (C7H3BrF3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3BrF3NO3 |
| Molecular Weight | 286.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-4-(trifluoromethoxy)nitrobenzene (CAS 1003708-31-3)
- 4-Bromo-1-nitro-2-(trifluoromethoxy)benzene (CAS 1260879-28-4)
- 5-Bromo-2-(trifluoromethoxy)nicotinic acid (CAS 1361803-33-9)
- 1-Bromo-2-(difluoromethoxy)-5-fluoro-4-nitrobenzene (CAS 1417566-72-3)
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- 4-Bromo-2-nitro-5-(trifluoromethyl)phenol (CAS 1613719-77-9)
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Recommended Standards
- 1-Bromo-4-nitro-2-(trifluoromethoxy)benzene (CAS 1807109-20-1)
- 1-Bromo-3-difluoromethoxy-2-fluoro-5-nitrobenzene (CAS 1807172-71-9)
- 1-Bromo-4-difluoromethoxy-3-fluoro-5-nitrobenzene (CAS 1807026-85-2)
- 1-Bromo-4-difluoromethoxy-5-fluoro-2-nitrobenzene (CAS 1807172-74-2)
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