5-Chloro-2-iodo-4-(trifluoromethoxy)aniline CAS 1807189-26-9
| CAS No. | 1807189-26-9 |
| Molecular Formula | C7H4ClF3INO |
| Molecular Weight | 337.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 337.47 g/mol gives 5-Chloro-2-iodo-4-(trifluoromethoxy)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-2-iodo-4-(trifluoromethoxy)aniline (CAS 1807189-26-9), molecular formula C7H4ClF3INO and molecular weight 337.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-2-iodo-4-(trifluoromethoxy)aniline (C7H4ClF3INO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3INO |
| Molecular Weight | 337.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-iodo-6-(trifluoromethoxy)aniline (CAS 1000802-17-4)
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- 2-Chloro-6-iodo-4-(trifluoromethoxy)aniline (CAS 1805237-24-4)
- 9-Chloro-2,3-dimethoxy-6-nitroacridine (CAS 6628-92-8)
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Recommended Standards
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- Danazol (CAS 17230-88-5)
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- 3-{[(3,4-dichlorophenyl)methyl]amino}propan-1-ol (CAS 103323-79-1)
- (2-ethyl-5-methyl-2H-1,2,3-triazol-4-yl)methanol (CAS 1864072-73-0)
- 3-Chloro-5-methyl-5H-pyrrolo[2,3-b]pyrazine (CAS 1111638-11-9)
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